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Fisetin - A Senolytic and Anti-Inflammatory Agent

Fisetin, a flavonoid found in fruits and vegetables, has been shown to eliminate senescent cells and reduce inflammation.

Daily Longevity Tip: Fisetin - A Senolytic and Anti-Inflammatory Agent

Tip Summary: Fisetin, a flavonoid found in fruits and vegetables, has been shown to eliminate senescent cells and reduce inflammation.

Hey Dog Longevity friends! An important tenet of supporting longevity is managing senescent cells (zombie cells). Today, let's explore the potential of Fisetin, a natural compound, as a senolytic and anti-inflammatory agent, and its possible effects on dog longevity. Let’s look at what fisetin is, how it can control senescent cells, benefits of use, and key takeaways:

What Is Fisetin? Fisetin is a natural flavonoid found in many fruits and vegetables, known for its senolytic properties. It's gaining attention for its ability to reduce cellular senescence and related inflammation.

Understanding Senescent Cells: Senescent cells accumulate with age and release inflammatory factors that degrade tissue health. Fisetin targets these cells, potentially reducing inflammation and slowing aging processes.

Benefits of Fisetin in Dogs:

  • Fisetin has shown promise in animal studies, notably in mice, for extending lifespan by 10%.

  • It could potentially slow down aging in dogs by reducing the number of senescent cells.

Where to Find Fisetin: Fisetin is found in fruits like strawberries, apples, and persimmons. Incorporating these into your dog's diet may provide health benefits.

Key Takeaways for Dog Parents:

  • Introducing fisetin-rich foods to your dog's diet might offer anti-aging benefits.

  • Keep in mind that research is ongoing, and fisetin supplements specifically for dogs are not yet available.

Sources: Fight Aging and NCBI

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